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CASE REPORT
Year : 2012  |  Volume : 21  |  Issue : 2  |  Page : 152-154

Augmenting amisulpride with clozapine had led to unmasking of akathisia


1 Department of Psychiatry, Calcutta National Medical College, Bankura, West Bengal, India
2 Department of Pharmacology, Bankura Sammilani Medical College, Bankura, West Bengal, India

Correspondence Address:
Anirban Ray
Flat 103/104, Sight Purabi Apartment, 19, Baishnabghata Lane, Kolkata - 700 047, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-6748.119638

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Amisulpride is a newer antipsychotic, which is very effective on its own, as well as augmenting other antipsychotic clozapine, which is an effective molecule for treatment resistant schizophrenia. In most cases, amisulpride is added on, in partial responders to clozapine. Here a case is reported where clozapine was added on, in an amisulpride partial responder but this produced side effect and had to be discontinued. The case later responded to clozapine alone. It has been discussed about possible reasons of this finding. It has also been suggested if sequence of introduction of medication is critical regarding getting the desired effect of the augmentation strategy.


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