Industrial Psychiatry Journal

CASE REPORT
Year
: 2019  |  Volume : 28  |  Issue : 2  |  Page : 321--324

Adjunctive dexmedetomidine for treatment of delirium tremens: Case report and brief review


Amit Chail1, Amresh Dubey1, Yujal Man Singh1, Nikahat Jahan2 
1 Department of Psychiatry, Command Hospital (Southern Command), Pune, Maharashtra, India
2 Department of Anaesthesia, AFMC, Pune, Maharashtra, India

Correspondence Address:
Dr. Amresh Dubey
Department of Psychiatry, Command Hospital, Pune, Maharashtra
India

Alcohol withdrawal delirium (delirium tremens [DT]) is a medical emergency. Gamma-aminobutyric acid type A agonists (benzodiazepines [BZDs]) are the mainstay of treatment. Resistant alcohol withdrawal requires adjunctive medications along with BZDs and supportive care. DT is associated with significant autonomic dysfunction (sympathetic hyperactivity). Dexmedetomidine is a selective a2-adrenergic receptor agonist which reduces sympathetic over-activity and agitation in delirious patients. We present a case of alcohol withdrawal delirium (DT) who responded well to adjunctive dexmedetomidine infusion resulting in reduced sympathetic activity and reduced dose requirement of BZDs.


How to cite this article:
Chail A, Dubey A, Singh YM, Jahan N. Adjunctive dexmedetomidine for treatment of delirium tremens: Case report and brief review.Ind Psychiatry J 2019;28:321-324


How to cite this URL:
Chail A, Dubey A, Singh YM, Jahan N. Adjunctive dexmedetomidine for treatment of delirium tremens: Case report and brief review. Ind Psychiatry J [serial online] 2019 [cited 2020 Dec 3 ];28:321-324
Available from: https://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2019;volume=28;issue=2;spage=321;epage=324;aulast=Chail;type=0